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Antoine Laurent Lavoisier, a ‘many-sided genius’, is
regarded as founder of modern chemistry. He is one of those scientists,
whose work actually led to the establishment of the foundations
upon which modern science rests. When Lavoisier started working
in chemistry it could hardly be called a distinct scientific discipline.
While there was a large mass of empirical information but there
was very little theoretical basis and it had no formal language
of its own. The characteristics of metals, salts, acids and alkalis
were well-known but gases were hardly known to exist. Modern chemistry
was born when Lavoisier, with the help other chemists, derived his
theory of combustion. While demonstrating the central role of oxygen
in combustion, Lavoisier disproved the phlogiston theory. Lavoisier’s
theory of combustion revolutionized the field of chemistry as a
whole. He clearly demonstrated the role of oxygen in respiration
of both animals and plants. He showed quantitatively the similarity
between respiration and combustion. He appreciated the importance
of measurements in chemistry. For making careful measurements, he
got balances constructed, which were of very high precision. Lavoisier’s
most sensitive Fortin balance was accurate to 1 part in 40,000.
Lavoisier’s use of measurements in experiments changed chemistry
from a science of observation to science of measurement. He established
the composition of water and many organic compounds. He clarified
the distinction between compounds and elements and provided a logical
system of chemical nomenclature. He made precise measurements of
the mass changes in chemical reactions. And in doing so he formulated
the law of conservation of mass, that matter is neither created
nor destroyed in chemical changes. Lavoisier laid the framework
for understanding chemical reactions as combination of different
substances. He also produced pioneering work on anatomy and physiology.
Lavoisier’s monumental achievements in chemistry
constituted only one of his many activities. It is interesting to
note that his public duties were so numerous that he could spare
only one day in a week for scientific investigations. He performed
many important administrative functions in the Royal Academy of
Sciences. He made significant improvements in the manufacture of
gunpowder. He wrote important papers on economics. As a member of
the Temporary Commission on Weights and Measurements (1791-93),
he played an important role in planning for the metric system. Lavoisier
made contributions to agriculture and demonstrated the advantages
of scientific farming at a model farm near Blois. In 1785 Lavoisier
was appointed as secretary to the Government’s committee on
agriculture. He drew up reports and instructions on the cultivation
of crops. He also promulgated various agricultural schemes. He was
a member of a committee concerned with social conditions of France
and he developed schemes for improving public education, equitable
taxation, savings banks, old age insurance and other welfare schemes.
Lavoisier served on a committee that explored hospitals and prisons
of Paris and then recommended remedies for their horrible state.
Lavoisier worked on a scheme for improving the water supply to Paris
and on a method for purifying water. During the Revolution he published
a report on the state of France’s finances. He had given money
without interest to the towns of Blois and Romorantin for the purchase
of barley during the famine of 1788. Politically Lavoisier was a
liberal. He saw the great necessity for reform in France and he
worked for it but he opposed revolutionary methods.
Lavoisier was born in Paris on August 26, 1743.
His father Jean-Antoine Lavoisier was a Parliamentary counsel (avocat
au parlement). His mother Emilie Punctis was the daughter of a wealthy
attorney. After the early death of his mother, Lavoisier was brought
up by a maiden aunt. He had a happy childhood. He studied at the
College Mazarin, in which he enrolled in 1754. At the College Mazarin
he studied mathematics and astronomy with Nicolas de Lacaille (1713-62),
chemistry with Guillaume-Francois Rouelle (1703-70) and botany with
Bernard de Jussieu (1699-1786). He received an outstanding education
in language, literature, science and mathematics. Following his
family tradition, he pursued the study of law and he finished his
education in the Faculty of Law in 1763. He obtained his license
to practice law in 1764. But his inquiring mind took him to the
world of science. First he studied geology (1763-67) under Jean
Etienne Guettard (1715-86), who was the first to prepare a geological
map of France. Lavoisier accompanied Guettard on several extensive
geological trips through various regions of France. Lavoisier assisted
Guettard in preparing Mineralogical Atlas and Description of France.
While going through these geological trips, Lavoisier realized the
close relationship between field mineralogy and the chemical analysis
of minerals. He set up a laboratory in his own home. In 1765 Lavoisier
published a paper on how to improve the street lighting of a large
city like Paris. For this paper he received a Gold Medal from the
Royal Academy of Sciences in 1766. In 1768 Lavoisier presented a
paper on the analysis of water samples. Following this he was admitted
to the Royal Academy of Science as adjoint-chimiste (associate chemist).
In his early days Lavoisier published research papers on the Aurora
Borealis, on thunder and on the composition of gypsum.
In 1768 Lavoisier became a member of a private
consortium called the Fermiers Generaux (Farmers General), which
had leased from the Government the right to collect some indirect
taxes for six years. This was to ensure a steady income for financing
his scientific investigations. Lavoisier had the wealth to invest
as through his family he had became independently wealthy as early
as in his early 20s. Lavoisier took his duties as tax collector
very seriously and spent much time away from Paris on inspection
duty. Lavoisier’s father bought him a title of nobility in
1772. In 1777 Lavoisier had purchased the country estate of Frechines
near Blois.
In 1771, Lavoisier married Marie-Anne-Pierette
Paulze (1758-1836). She was 14 at the time of her marriage with
Lavoisier. Her father was a colleague of Lavoisier in the Farmers
General. Marie Paulze’s mother was a niece of Abbe Terray,
France’s Controller General of Finances and one of the most
influential men of the French kingdom. Lavoisier’s marriage
with Marie Paulze proved to be very successful. She was a skilled
artist, engraver and painter. She studied under Louis David (1746-1825),
who painted the only known portrait of Lavoisier from life. She
kept laboratory records and made sketches of her husband’s
experiments. She learnt English and Latin. She translated the new
chemical treatises from England, which included the works of Priestley
and Cavendish. Ray Spangenburg and Diane K. Moser wrote: “Lavoisier
was a mover in the scientific world; although his money came to
be sure, from the Fermiers Generaux, he spent it lavishly in the
interest of science, and his private laboratory was a meeting place
for all the major scientific figures of Europe. Thomas Jefferson
and Benjamin Franklin both were warmly welcomed there. Lavoisier’s
wife, Marie-Anne, who married him when she was 14, attended these
meetings, illustrated them for Lavoisier’s books and was always
deeply involved in his work. She translated works from English for
him, took notes and participated actively.”
Lavoisier, after being appointed to the National
Gunpowder Commission in 1775, shifted his residence to the Royal
Arsenal of Paris. At the Arsenal, Lavoisier was in effective charge
of gunpowder production and research. He was appointed as a director
of the gunpowder administration (regisseur des poudres). Before
Lavoisier took charge of the gunpowder administration in France,
it was in a very chaotic state. He greatly improved the gunpowder,
its supply and manufacture. Lavoisier abolished the vexatious search
for saltpetre in the cellars of private house. He also built an
excellent laboratory of his own in his home. His new home became
a gathering place for scientists and freethinkers. After dinners,
which used to be presided over by his wife, the guests often used
to be escorted to the laboratory to witness demonstration of new
experiments. One of Lavoisier’s co-workers at the Arsenal
was Pierre Simon Laplace (1749-1827). Lavoisier, with the help of
Laplace, extended Joseph Black’s early work on calorimetry.
They developed an ingenious ice calorimeter and with this they measured
heats of combustion and respiration. It was a modified version of
Black’s calorimeter. This was the beginning of thermochemistry.
They also derived an apparatus for measuring linear and cubical
expansions. It may be noted here that Eleuthere Irenee du Pont (1771-1834)
was an assistant to Lavoisier at the Arsenal. Du Pont later migrated
to the USA (1800) and in 1802 he established a factory on the banks
of the Brandywine River in Delware for making gunpowder. This venture
of du Pont later developed into one of the world’s largest
chemical concerns.
Lavoisier is best known not for his major experiments
or discoveries but for his synthesis of the existing chemical knowledge.
Much of Lavoisier’s work was the result of extending and coordinating
the research of others. He interpreted and organized the experimental
results of others and whenever necessary substantiated by his own
experiments. Justus von Liebig (1803-73), the great German chemist,
said that Lavoisier “discovered no new body, no new property,
no natural phenomenon previously unknown. His immortal glory consists
in this—he infused into the body of science a new spirit.”
Lavoisier could achieve all this because he was not working as an
isolated scientist. He was the focus of a school of collaboration.
He was an important member of France’s Royal Academy of Sciences—the
world’s most impressive assemblage of scientists. He was also
an important public figure—he was at the centre of efforts
to reform the French political economy.
In 1777 Lavoisier published a paper on respiration.
The title of the paper was “Experiments on the respiration
of animals and on the changes, which the Air undergoes in passing
through the lungs.” Lavoisier demonstrated that respiration
was a slow combustion or oxidation. The process of respiration used
oxygen and released carbon dioxide. In his Memoir of Heat, Lavoisier
wrote: “the heat released in the conversion of pure air by
respiration is the principal cause of the maintenance of animal
heat.”
In 1783, Lavoisier, jointly with Claude Berthollet,
Antoine Francois de Fourcroy and L. B. Guyton de Morveau, published
Methode de nomenclature (System of Chemical Nomenclature). It proposed
new names for elements. The need for an international nomenclature
consistently reflecting the composition of substances became evident
to Lavoisier when he was asked to write an article on history of
chemistry for an encyclopedia. Before Lavoisier the language used
in chemical texts was full of inconsistencies, imprecision and double
meanings. The terms used in old alchemical and chemical texts were
drawn from many languages – Greek, Hebrew, Arabic and Latin.
The names of chemical substances were based on a variety of analogies
and impressions. A few examples of the terms used in early chemical
and alchemical texts are indicated below:
Flowers of Zinc Zinc Oxide
Oil of Vitriol Sulphuric acid
Spanish Green Copper acetate
“Father” Sulphur
“Mother” Mercury
Lavoisier suggested that the elements in a compound
should be reflected in its name. Based on this suggestion ‘Flowers
of zinc’ became zinc oxide (a compound of zinc and oxygen)
and ‘oil of vitriol’ became sulphuric acid), a compound
of sulphur, oxygen and hydrogen). The new system of nomenclature
proposed by Lavoisier had a provision for indicating relative proportions
of the elements in a compound, for example sulphurous acid contains
less oxygen than sulphuric acid.
In 1789 Lavoisier published Traite elementair de
chimie (Elementary Treatise on Chemistry). Many consider it as the
first textbook on modern chemistry. While Lavoisier not only designed
this book for beginning students but in it he also used his own
experiments and discoveries to redefine the content and practice
of chemistry. It beautifully summarized Lavoisier’s main experiments
and theories on which he based his movement to revolutionise chemistry.
It incorporated the earlier knowledge of chemistry of salts into
the new framework. In this book Lavoisier described in detail the
experimental basis for his rejection of phlogiston theory in favour
of his own theory of oxygen. In this book Lavoisier presented his
definition of an element, as ‘the last point which analysis
can reach.’ Lavoisier conclusively rejected the four-element
theory, an idea that dated back to Empedocles and Aristotle. According
to this theory everything was believed to be composed of earth,
air, fire and water combined in different proportions. Each of these
supposedly element represented different pairs of essential qualities—earth
the cold and dry; water, cold and weight; fire, hot and dry; and
air, hot and weight. It used to be believed that an important consequence
of four-element theory was that water could be converted into earth.
Lavoisier refuted this claim without any scope of doubt. The contained
a list of 33 elements known at that time. His list included metallic
and nonmetallic solids, earthy substances; the gases oxygen, nitrogen
(then called azote), and hydrogen; and light and heat (caloric).
Lavoisier’s list of elements provided the basis from which
modern periodic table of elements has grown. The book had such an
enormous influence on chemistry that it is compared with Newton’s
Prinicipia in physics.
Lavoisier, based on his own experiments and by
interpreting the experimental results obtained by others, worked
out a theory of combustion. Before Lavoisier it was phlogiston theory,
which explained combustion. Lavoisier also went on to show that
air is a mixture of two gases—oxygen and nitrogen (he called
it azote). Of course, now we know that air contains other gases
also. But before Lavoisier air was considered a single substance
and not a mixture. Lavoisier showed that it was oxygen which supported
combustion. The phlogiston theory was the first comprehensive theory
of chemistry. Its chief proponent was Georg Ernst Stahl. The term
“phlogiston” was coined by Stahl from the Greek word
for “inflammable.” Stahl used this term for the first
time in his treatise (1697), in which he sought to distinguish combustion
from fermentation. In the seventeenth century chemists generally
believed that some combustible substances contain an “inflammable
principle.” And when such substances burn this so called inflammable
principle is released. Stahl sharpened this concept. He equated
the inflammable principle or phlogiston with elementary principle,
as fire was thought in those days. Phlogiston could not be obtained
in isolation. Stahl reasoned that sulphur was composed of vitriolic
acid and phlogiston because it could be produced by treating vitriolic
acid with charcoal, a phlogiston-rich substance. Similarly metals
are made of their oxides (calxes) and phlogiston as oxides could
be converted back into metals by heating with charcoal. Stahl’s
ideas about phlogiston came to be known as phlogiston theory. This
theory stated that combustion was a loss of substance called phlogiston.
And so the residue or ash was composed of the original material
deprived of its phlogiston.
Phlogiston was regarded a weightless or nearly
weightless substance. Though the phlogiston theory was derived from
an erroneous concept it helped to explain innumerable puzzling chemical
phenomena. For chemists of those days the phlogiston theory became
an important means of organizing otherwise disconnected observations
into a coherent body of knowledge. It stimulated all kinds of experiments
on combustion, on oxidation, on respiration and on photosynthesis.
While carrying out these experiments chemists came across many phenomena,
which could not be explained by resorting to the phlogiston theory.
It was found that when some metals were calcined, the resulting
calx was heavier than the initial metal. Supporters of phlogiston
theory tried to explain this phenomenon by proposing that in some
metals, phlogiston had negative weight. It was found that the red
precipitate of mercury (mercury oxide) could be turned back into
a metal simply by heating. This implied that no phlogiston-rich
source such as charcoal was needed. In spite of these problems most
chemists of eighteenth century did not discard the phlogiston theory
and while subscribing to this erroneous theory they made pioneering
contributions particularly to the study of gases.
In a series of experiments carried out during 1772-74,
Lavoisier burned phosphorus, lead, sulphur, and other elements in
closed containers. While carrying out these experiments Lavoisier
found that while the weight of the solid increased but the weight
of the container and its contents remained same. The immediate consequence
of this observation was that some part of the whole system must
have lost weight. The most probable candidate for this was the air
present in the vessel. Now if air lost something, a partial vacuum
would exist in the closed vessel. This is because the experiment
was carried out in a closed vessel. This was exactly what was found
by Lavoisier. When he opened the vessel, the air rushed in to fill
up the vacuum. And after this when Lavoisier weighed the container
and its contents he found that the weight increased than the original.
It clearly demonstrated that the formation of the oxide (or calx)
was the result of the combination of air and the metal. The weight
increased because of the gain of air and not due to loss of phlogiston.
Lavoisier also discovered that the gas generated by heating an oxide
(calx) with charcoal was nothing but fixed air earlier discovered
by Joseph Black.
It was from Joseph Priestley’s experiments
that Lavoisier got the idea that oxygen supported combustion. Priestley
had discovered oxygen. However, he could not realize the full significance
of his discovery. Lavoisier correctly interpreted the discovery
made by Joseph Priestley.Even before Priestley, Pierre Bayen, an
apothecary in the French army, isolated oxygen. In 1774 Bayen observed
that red precipitate of mercury (mercuric oxide or HgO) produced
a gas when it was heated. Bayen identified it ‘fixed air’
(CO2) earlier produced by Joseph Black. Soon after Bayen’s
demonstration Priestley repeated Bayen’s experiment, probably
independently. Priestley’s experiments identified the chemical
nature of the gas. Priestley observed that the gas, produced by
the red precipitate of mercury, supported combustion better than
the normal air. As Priestley believed in phlogiston theory, he called
this new air phlosisticated air. The properties of Priestley’s
new air seemed to be exactly the reverse of Black’s dephlogisticated
air. He also found that breathing it “peculiarly light and
easy.” It may also be noted that Carl Wilhelm Scheele (1742-86),
a Swedish chemist, also discovered the same gas. He called it ‘fire
air’ and he postulated that fire air was part of atmospheric
air. However, Scheele’s discovery was published later. Lavoisier
was quick to see the significance of new findings. After knowing
Priestley’s experiment, Lavoisier immediately recognized its
true significance. He realized that Priestley had isolated one part
of the air that supports combustion and respiration and other part
of the air does not. In 1779 Lavoisier finally announced that the
air is composed of two gases—one that supports combustion
and the other gas does not support combustion. The part that supported
combustion, Lavoisier named oxygen, a name derived from Greek roots
meaning “to give rise to acids.” He thought all acids
contain oxygen. Here Lavoisier was proved to be wrong later. It
was one of those rare occasions when Lavoisier was wrong. Though
Lavoisier proved wrong the name “oxygen” has been retained.
The other gas he named “azote” again from Greek root
meaning “no life”. Unlike oxygen, azote was renamed
nitrogen in 1790.
Priestley lived in Leeds, a city in north England.
He was a Unitarian minister. A Unitarian is a person who denies
the doctrine of Trinity—the union of three divine persons
Father, Son, and Holy spirit) in one Godhead and believes that God
exists in one person or being. A Unitarian accepts the moral teachings,
but rejects the divinity of Jesus. In his political belief Priestley
was a radicalist. He supported the American colonists when in 1776
they revolted against George III (1760-1820), King of Great Britain
and Ireland (1760-1820). He was against slave trade and religious
bigotry. Priestley sympathised with the French Revolution. He began
his scientific experiments in a local brewery of the city of Leeds.
In 1780, Priestley moved to Birmingham, where he became a member
of the Lunar Society. Other member of this society included Erasmus
Darwin (1731-1802), James Watt and Matthew Boulton. In Birmingham,
Priestley built an elaborate laboratory, which was considered by
many as one of the best laboratories of that time in Europe. It
may be noted that on the day of Lavoisier’s execution at the
Guillotine, Priestly was forced to leave England for safety. For
his support to revolutionaries in France, the rioting anti-revolutionaries
burnt down his house. He spent his last ten years of his life in
USA.
Thomas Kuhn in his much discussed book, The Structure
of Scientific Revolution, cited Lavoisier’s revolution in
chemistry as a major example of scientific revolutions and paradigm
shift. While many tend to agree with Kuhn but then there are some
who fail to see how Lavoisier’s chemistry provided an example
to support Kuhn’s theory. Because even after Lavoisier proposed
his combustion theory, chemists took a long time to abandon the
phlogiston theory in favour of Lavoisier’s theory. It was
certainly not a sudden change.
It was Lavoisier, who first showed that all substances
can exist in the three stages of matter--solid, liquid and gas.
He believed that those changes in state were the result of fire
combining with matter. Lavoisier thought that the “matter
of fire” or caloric, as he called it, was weightless and combined
with solid to form liquid and combined with liquid to form gas.
Lavoisier in his Memoir on Combustion in General published in 1777
wrote: “Undoubtedly it will not amiss to ask first what is
meant by the matter of fire. I reply with Franklin, Boerhaave, and
some of the philosophers of antiquity that the matter of fire or
of light is a very subtle, very elastic fluid which surrounds all
parts of the planet which we inhibit, which penetrates bodies composed
of it with greater or less ease, and which tends when free to be
in equilibrium in everything.
I will add, borrowing the language of chemistry,
that this fluid is the dissolvent of a large number of bodies; that
it combines with them in the same manner as water combines with
salt and as acids combine with metals; and that the bodies thus
combined and dissolved by the igneous fluid lose in part the properties
which they had before the combination and acquire new ones which
make them more like the matter of fire.”
Reign of Terror in France did not spare Lavoisier,
one of the greatest scientists of all times. As a tax collector
of the Government that was deposed by the revolutionary forces,
many considered Lavoisier as public enemy. After all, they argued,
he was member of the agency, which collected taxes from poor and
downtrodden populace for an unpopular king. Lavoisier’s problem
compounded when Jean-Paul Marat gained power in the revolutionary
government and became a key force in the Reign of Terror that washed
the streets of Paris in blood. Marat was a journalist who had early
in his career pursued scientific ambition and he fancied himself
a scientist. Lavoisier had condemned Marat’s worthless pamphlet
Physical Researches on Fire and he had also opposed the admission
of Marat to the French Academy of Sciences. Marat had never forgotten
this. Lavoisier had been arrested alongwith all members of the Farmers
General were arrested and thrown into prison. Though the tax collecting
farm was a natural target but it affairs were in good order and
the charges against its members could be refuted. But Marat wanted
to punish Lavoisier. A new charge of ‘counter revolutionary
activity’ was contrived which ensured a guilty verdict. In
1787, at Lavoisier’s suggestion a wall was erected was erected
to stop the influx of contraband. The extremist revolutionaries
charged Lavoisier of imprisoning Paris and stopping the circulation
of air. In 1791 the Farmers General was abolished and not long after
Lavoisier was removed from his post in gunpowder administration
and he was forced to leave the arsenal. Lavoisier was arrested in
November 1793. On May 08, 1794 after a trial that lasted less than
a day Lavoisier was guillotined. Along with him his father in law
and other members of the Farmers General were also executed. Lavoisier’s
estate was confiscated, including his library and laboratory instruments.
His wife Marie-Anne was also imprisoned but later released. She
took refuge with a family servant. Marat who was instrumental in
getting Lavoisier and other members of Farmers General convicted,
himself was was arrested and guillotined before Lavoisier. But that
did not help Lavoisier. It has been reported that Lavoisier requested
time to complete some scientific work. His request was refused and
the presiding judge was said to have answered, “The Republic
has no need of scientists.” Joseph Louis Lagrange said: “It
took but a moment to cut off that head: perhaps a hundred years
will be required to produce another like it.”
After Lavoisier’s execution, his wife petitioned
for the return of his estate. And after obtaining Lavoisier’s
papers and books, she took up the task of publishing Lavoisier’s
unfinished memoirs. Thus Lavoisier’s Memoires de chimie or
Memoirs of Chemistry were published in two volumes in 1803. She
presented copies to the important scientific societies and eminent
scientists of Europe. As in the days when Lavoisier was alive, her
home also became a meeting place to the leaders of science in France.
Jean Baptiste Joseph Delambre (1749-1822), Baron Georges Lepold
Chretien Frederic Dagobert Cuvier (1769-1832), Comte Joseph Louis
Lagrange (1736-1813), Marquis Pierre Simon de Laplace (1749-1827),
Pierre Eugene Marcellin Berthollet (1827-1907), Dominique Francois
Jean Arago (1786-1853), Jean Baptiste Biot (1774-1862), Alexander
von Humboldt (1769-1859) and others attended meetings at her home.
She refused to attend those whom she thought did not use their political
connections to save her husband. In 1804 Marie-Anne married Count
Rumford. She kept Lavoisier’s name after her marriage to Rumford.
At the time of her marriage to Rumford, she was 47 and Rumford was
50. Her second marriage did not go well and it lasted for only four
years.
Lavoisier’s life ended at the whims of some
lunatics but the great revolution in chemistry ushered in by him
did not stop there. “With Lavoisier’s death in 1794,
his part in the great revolution came to a conclusion, but progress
did not end there. From the foundations laid by Lavoisier, Black,
Scheele, Priestley, Cavendish and, in a way, even Stahl, chemists
in the 19th century were able to build an ever-more-accurate understanding
of chemical elements, their nature, how they react with one another
and what processes take place in those reactions.”
References
- The History of Science in the Eighteenth Century by Ray Spangenburgh
and Diane K. Moser. Hyderabad: Universities Press (India) Limited,
1999.
- Chambers Biographical Dictionary (Centenary Edition), edited
by Melanie Parry. Edinburgh and New York: Chambers Harrap Publishers
Limited, 1997.
- The Cambridge Dictionary of Scientists (2nd Edition) by David,
Ian John & Margaret Millar. Cambridge: Cambridge University
Press, 2002.
- A Dictionary of Scientists. Oxford and New York: Oxford University
Press, 1999.
- The Oxford Companion to The History of Modern Science, edited
by J. L. Heilborn. Oxford: Oxford University Press, 2003.
- The New Encyclpaedia Britannica (15th Edition). Chicago: Encyclopaedia
Britannica, Inc, 1994.
- Antoine Lavosier : Science. Administration, and Revolution
by Arthur L. Donovan, Oxford (England) and Cambridge: Massachusetts.
Blackwell Science Biographies, 1993.
- Lavosier and the Chemistry of life : An Exploration of Scientific
Creativity by Frederic Lawrence Holmes. Wisconsin Publications
in the History of Science and Medicine . 4. Madison and London
: University of Wisconsin Press, 1985.
- Revolution in Science by I Bernard Cohem. Cambridge, Massachusetts
: Belknap Press of Harvard University Press, 1985
List of Illustrations
- Antine Laurent Lavoisier
- Lavoisier and is wife
- Antoine Lavoisier and his wife, Marie-Anne, presiding at the
death of phlogiston (courtesy, Park Davis, Division of Warner-Lambert
Company)
- Lavoisier demonstrating the composition of air (Figure: Vies
des savants, 1870)
- An experiment in Lavoisier’s laboratory drawn by his
wife.
- Pierre Simon Laplace
- E. I. Du Pont
- Claude Berthollet
- Antoine Francois de Fourcroy
- L. B. Guyton de Moreau
- Georg Ernst Stahl
- Joesph Priestley
- Joseph Black
- Carl Wilhelm Scheele
- Henry Cavendis
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